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Helps to maintain immune function. Source of amino acids . Provides precursor amino acids for Glutathione which are also involved in muscle protein synthesis. Antioxidant that helps protect against oxidative stress.


UNIQUE bio-compatible Glutathione source

IMMUNE support - super antioxidant

LIVER support and detoxification

MUSCLE support

Glutathione (GSH) may be the most important molecule needed to boost your immune system and prevent oxidative stress (a major cause of chronic illnesses and disorders).

Supplemental glutathione, even in its widely available 'reduced' form, is very poorly absorbed in the intestine because of its molecule size. Our research has shown the best solution to efficiently boost glutathione levels is to generate it endogenously (internally) by fermentation in the gut, while simultaneously supplying easy to absorb precursors to synthesize it in the liver.

Endothione™ contains a masterful molecular blend of ingredients that start a unique gut fermentation process to produce bio-compatible glutathione, easily recognized, absorbed and utilized by the body. We have also added Selenium as a catalyst for the breakdown of hydrogen peroxide and organic hydroperoxides, and Zinc, a well known immune function booster.

The ingredients are encapsulated in a delayed release (DR) vegetarian capsule that minimizes the impact of stomach acids and maximizes ingredient absorption.


  • Pietro Ghezzi; Role of glutathione in immunity and inflammation in the lung; Int J Gen Med. 2011; 4: 105–113.
  • Hamilos DL, Zelarney P, Mascali JJ.; Lymphocyte proliferation in glutathione-depleted lymphocytes: direct relationship between glutathione availability and the proliferative response. Immunopharmacology. 1989 Nov-Dec;18(3):223-35.
  • Carlos Guerra et al.; Glutathione and Adaptive Immune Responses against Mycobacterium tuberculosis Infection in Healthy and HIV Infected Individuals; PLoS One. 2011; 6(12): e28378.
  • Witsky et al.; The Systemic Availability of Oral Glutathione; European Journal of Clinical Pharmacology; (1992) 43:667-669
  • Rajagopal V Sekhar et al.; Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation; Am J Clin Nutr 2011;94:847–53
  • Rajagopal V Sekhar et al.; Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine; DIABETES CARE, VOLUME 34, NUMBER 1, JANUARY 2011
  • Kullisaara et al.; Complete Glutathione System in Probiotic Lactobacillus fermentum ME31; Applied Biochemistry and Microbiology, 2010, Vol. 46, No. 5, pp. 481–486
  • Peran L. et al.; Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis; Int J Colorectal Dis. 2006 Dec;21(8):737-46


Did you know

The human body synthesizes its own Glutathione, but as we grow older, our internal Glutathione levels drop due to genetics, disease, environment, and many other factors beyond our control.

Directions & Cautions

Who can benefit?

All adults concerned with the body's aging process, and wanting to feel and look younger.

As part of an anti-aging protocol/program

Before gym or exercise activity

Recommended dose

Adults take 2 capsules one time per day.


For prolonged use, consult a health care practitioner. If symptoms persist or worsen, or if new symptoms develop, discontinue use and consult a health care practitioner. Ensure to drink enough fluid before, during, and after exercise. Consult a health care practitioner prior to use if you have diabetes, a history of cancer, or suffer from an immune system disorder (e.g. Crohn's disease, myasthenia gravis, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematous, HIV/AIDS, etc.) or you are taking medications to suppress the immune system (immunosuppressive medications) If you are taking prescription medications, consult a health care practitioner prior to use. Do not use this product if you are pregnant or breastfeeding or if have a known allergy/hypersensitivity to cow's milk. May cause a flushing, tingling and/or prickling sensation of the skin, in which case, reduce the dose.

Do not use if seal is broken. Keep out of reach of children.

Keep sealed, store in a cool, dry place at 15–25ºC.

Restorative Health

Given the right nutraceutical support, the human body can repair itself and can also restore the immune system to its full capacity. Provita’s continuously evolving Restorative Health series, curated from the highest quality sources, is specially formulated to help the body increase its capacity to repair and restore.